Constraint-induced movement therapy: trial sequential analysis applied to Cochrane collaboration systematic review results

Constraint-induced movement therapy: trial sequential analysis applied to Cochrane collaboration systematic review results

BACKGROUND Trial sequential analysis (TSA) may establish when firm evidence about the efficacy of interventions is reached in a cumulative meta-analysis, combining a required information size with adjusted thresholds for conservative statistical significance. Our aim was to demonstrate TSA results on randomized controlled trials (RCTs) included in a Cochrane systematic review on the effectivene...

Constraint-induced movement therapy in stroke patients: systematic review and meta-analysis.

AIM Upper extremity paresis is a leading cause of disability after stroke. A Cochrane review found an impact on disability of Constraint-Induced Movement Therapy (CIMT), its modified forms (mCIMT) and Forced Use (FU), with a moderate significant effect and a large significant effect on arm motor function. This article aims to present an update of the Cochrane review and assess the effects of CI...

Constraint-induced movement therapy.

Kunkel and colleagues 1 recently published an article on constraint-induced (CI) movement therapy for motor recovery in chronic stroke patients. They presented the results of an uncontrolled series of 5 stroke patients undergoing CI therapy. The authors also presented a review of five studies, including their own, concerning the effectiveness of CI therapy based on a calculation of effect sizes...

Constraint Induced Movement Therapy

Constraint-induced movement therapy.

Constraint-induced movement therapy improves outcome after chronic stroke, conforms experimental observations of neuronal plasticity, and proves the efficacy of intensive occupational therapy. More acutely instituted constraint-induced movement therapy has both practical and theoretic risks and benefits that deserve further careful evaluation.